I don’t see how this would be helpful.
From a sales perspective, just cite the existing literature for whatever compound(s). Meta-analysis won’t help much.
From a science perspective, no one will believe it (with or without a meta-analysis) until you have experimental data supporting the final cocktail improving longevity. Too many potential interactions, etc.
This is a clinical trial, then. I’m all for running decentralized clinical trials by mailing random pills to anons on the internet and convincing them to mail in blood or bloodwork results.
However, there are a ton of legal issues and design/statistics requirements around a clinical trial, and human subjects approvals are required for it in Switzerland, Canada and US. You can apply for NIH grants whose express purpose are designing clinical trials, so this is not trivial.
I would note that it would be easier to build the infrastructure (enrolling, vetting participants) for such a trial by starting with fitness challenges that may not require human subjects approval-- things like fasted cardio or not as the earlier example I used that you didn’t like.
Member base is too small for this. Do the math and the demand test before even worrying about what goes in the cocktail. What margin do you need per unit, and how many monthly purchases do you need of that unit to make it worthwhile vs how many members are there vs how many members would pay for it?
For some quick math, there are 3600 $Vita holders. If 10% of those buy your product, you are trying to build the treasury off 360 monthly purchases. Let’s assume you can sell the month supply for $30. That’s $130k/year in total revenue. Not profit. Total revenue.
If the goal is to raise money for the treasury, you have to sell to normies. Then you’re taking the VitaDAO brand and turning it into part of the supplement business. I’m not saying a pivot from scienceDAO to longevity pill eCom DAO is bad, but that is what happens if the pill is successful.
Nothing in the proposal sounds like market research, which is what it sounds to me like you’re proposing is the purpose.
Overall, I think this could be modified into two distinct proposals.
Proposal 1) Sink $50k into spinning up an eCom business focused on creating a longevity supplement (ie no Rx). Keep the team lean, and give them a total 40% equity (tokenized and private, or not tokenized) in the biz as their pay. If any are US based, provide the docs for the 83b election, or similar tax advantages if such exist in Canada/Switzerland/etc. You can probably do this anon if the US based team members set up a Wyoming LLC, and Molecule or VitaDAO contracts with the LLC. No idea how it works in other countries.
First deliverables are a landing page, paid ads, content as needed, and a demand test to gauge interest and target audience. No go until the paid ads and landing page/site generate the necessary demand.
Second deliverables are content pages about compounds and activities that promote longevity, proposed formulation as a supplement blend, and manufacturer. Formulation then needs to be tested on members/volunteers and tweaked for taste, appearance, water solubility, etc. Once optimized, launch and focus everything on increasing revenue, and then slowly disburse back to the team/VitaDAO as it scales.
Proposal 2) Develop a decentralized or web-based system to enroll human participants in health challenges, and measure biomarkers. Maybe Vita membership is part of this. Maybe not. But build the infrastructure from which decentralized clinical trials could be launched. There are a ton of influencers who could convince people to enroll in a clinical trial if they believed in it or were curious about it. Fitness X in particular. this will drive the engagement you want. 4 week, 8 week, 10 week challenges are fun, and keep people talking.
The main challenge is logistic-- getting an interface, getting people to enroll, getting people to follow the #&#* protocol, collecting data, vetting data, and then handling biospecimens, mailing supplements, etc. But this could be built as a platform, and revenue come to the DAO from allowing others to use it (possibly in a permissionless manner if we stay true to web3 ethos). It would be a web3 clinical trial fundamental, much like the IPT is a web3 IP fundamental.
In the meantime, brainstorming the best Rx longevity cocktail can be done, and then an IPT for that, if possible. But need experimental data and/or clinical trial infrastructure first. Also, not sure if combos are harder to patent due to ‘obviousness’ and overlap with existing patents, especially if both drugs show activity.
